Alkyne Synthesis Reactions Practice Problems

The first practice problem is a summary of alkyne reactions, followed by comprehensive synthesis practice problems; all the major classes of alkyne and alkene reactions are covered!
These include the preparation of dialkyl halides and their use in the preparation of Alkynes by Elimination Reactions, Hydrohalogenation, Hydration, HydroborationOxidation, Ozonolysis, and other reactions of Alkynes and Alkenes, including the Zaitsev and Hoffman elimination reactions.

In addition, the synthetic strategies of changing the position of the double bond and extending the carbon chain by Alkylation of Terminal Alkynes are also demonstrated.

These examples guarantee a mastery level of alkyne and alkene reactions!

 

 

 

 

Practice

1.

Identify the reagents for each of the following reactions of internal and terminal alkynes:

Answer

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2.

On the following synthetic scheme, identify the reagents, in the correct order, that you would use to achieve the following synthetic transformations. Determine the structure of compounds A and B and the major organic products resulting from the alkyne.

Answer

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Solution

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3.

Suggest reagents for the following synthetic transformations of alkenes and alkynes:

 

a)
Answer

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b)
Answer

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c)
Answer

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d)
Answer

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4.

Use no other source of carbon to achieve the following synthetic transformations:

 

a)
Answer

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b)
Answer

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5.

Propose a plausible synthetic conversion of the following alkyne:

Answer

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Solution

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6.

Add the reagents, in the correct order, to achieve an efficient synthesis for each of the following multistep transformations.

a)
Answer

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b)
Answer

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c)
Answer

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d)
Answer

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e)
Answer

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f)
Answer

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Solution

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7.

Identify the missing reagents and products in the following synthetic scheme:

Answer

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8.

Identify the missing reagents and products in the following synthetic scheme:

 

Answer

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9.

Identify the missing reagents and products in the following synthetic scheme:

Answer

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10.

Bonus Question! Which fish is going to click?

 

 

Answer

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